2-[(3-Aminoalkyl-(alkaryl-,aryl-))-1 H-1,2,4-triazol-5-yl]anilines: Synthesis and anticonvulsant activity
Số trang: 10
Loại file: pdf
Dung lượng: 456.57 KB
Lượt xem: 4
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
The presented work is devoted to the development of synthesis methods for novel 2-[(3-aminoalkyl-(alkaryl-, aryl-))-1H -1,2,4-triazolo]anilines. Abovementioned compounds were obtained via hydrazinolysis (Ing-Manske procedure) and acid hydrolysis of corresponding N -acylated{([1,2,4]triazolo[1,5- c ]quinazolin-2-yl)alkyl-(alkaryl-, aryl-)}amines. The regioselectivity of hydrazinolysis and hydrolysis were established. The features of spectral characteristics were studied and discussed. Characteristic patterns of protons signals splitting in 1H NMR of the synthesized compounds were established. The effect of the synthesized compounds on the pentylenetetrazol seizures was studied.
Nội dung trích xuất từ tài liệu:
2-[(3-Aminoalkyl-(alkaryl-,aryl-))-1 H-1,2,4-triazol-5-yl]anilines: Synthesis and anticonvulsant activity
Nội dung trích xuất từ tài liệu:
2-[(3-Aminoalkyl-(alkaryl-,aryl-))-1 H-1,2,4-triazol-5-yl]anilines: Synthesis and anticonvulsant activity
Tìm kiếm theo từ khóa liên quan:
Journal of Chemistry Acidic hydrolysis Anticonvulsant activity Experimental seizures models Active oxygen formsGợi ý tài liệu liên quan:
-
14 trang 19 0 0
-
9 trang 18 0 0
-
Influence of magnetic field on properties of electrodeposited FeCo layer
5 trang 16 0 0 -
20 trang 15 0 0
-
Removal of Cr(VI) from wastewater through glycine assisted synthesis of TiO2
9 trang 14 0 0 -
Electrophoretic deposition and characterization of self-doped SrTiO3 thin films
10 trang 14 0 0 -
The effect of starting material types on the structure of graphene oxide and graphene
14 trang 13 0 0 -
Spectroscopic investigation of defect-state emission in CdSe quantum dots
8 trang 13 0 0 -
Tuning the mechanical properties and degradation properties of polydioxanone isothermal annealing
15 trang 13 0 0 -
The role of diazacrown ether in the enhancement of the biological activity of silver nanoparticles
11 trang 12 0 0