Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA
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InEscherichia colithe codons CGG, AGG, UGG or GGG (NGG codons)but not GGN or GNG (where N is non-G) are associated with low expres-sion of a reporter gene, if located at positions +2 to +5. Induction of alacZ reporter gene with any one of the NGG codons at position +2 to+5 does not influence growth of a normal strain, but growth of a strainwith a defective peptidyl-tRNA hydrolase (Pth) enzyme is inhibited.
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Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA
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Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA
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