Báo cáo khoa học: Abstract P1 – FEBS Datta Plenary Lectureship Award P1-001 Peptide bond formation, cotranslational folding and antibiotics synergism
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Ribosomes position their substrate at stereochemistry suitable forpeptide bond formation, and promote substrate-mediated cata-lysis. The linkage between substrate orientation, dominated byremote interactions, and a sizable symmetrical region identified inall known ribosome structures indicates a guided rotatory motionof aminoacylated-tRNAs along a ribosomal path leadings to theadvance of nascent peptides into the protein exit tunnel at anextended conformation.
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Báo cáo khoa học: Abstract P1 – FEBS Datta Plenary Lectureship Award P1-001 Peptide bond formation, cotranslational folding and antibiotics synergism
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Báo cáo khoa học: Abstract P1 – FEBS Datta Plenary Lectureship Award P1-001 Peptide bond formation, cotranslational folding and antibiotics synergism
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