Báo cáo khoa học: Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase
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Aloesone synthase (ALS) and chalcone synthase (CHS) are plant-specifictype III poyketide synthases sharing 62% amino acid sequence identity.ALS selects acetyl-CoA as a starter and carries out six successive condensa-tions with malonyl-CoA to produce a heptaketide aloesone, whereas CHScatalyses condensations of 4-coumaroyl-CoA with three malonyl-CoAs togenerate chalcone.
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Báo cáo khoa học: Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase
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Báo cáo khoa học: Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase
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