Báo cáo khoa học: Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages
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Exposure to quartz particles induces a pathological process named silicosis.Alveolar macrophages initiate the disease through their activation, which isthe origin of the later dysfunctions. Ascorbic acid is known to selectivelydissolve the quartz surface. During the reaction, ascorbic acid progressivelydisappears and hydroxyl radicals are generated from the quartz surface.These observations may be relevant to mammalian quartz toxicity, as sub-stantial amounts of ascorbic acid are present in the lung epithelium. ...
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Báo cáo khoa học: Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Ascorbic acid-pretreated quartz enhances cyclo-oxygenase-2 expression in RAW 264.7 murine macrophages
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