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Báo cáo khoa học: Identification and expression analysis of an IL-18 homologue and its alternatively spliced form in rainbow trout (Oncorhynchus mykiss)

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A homologue of interleukin 18 has been identified fromrainbow trout,Oncorhynchus mykiss. The trout IL-18genespans 3.7 kb and consists of six exons and five introns,sharing the same gene organization with its human coun-terpart. The putative translated protein is 199 amino acidsin length with no predicted signal peptide. Analysis of themultiple sequence alignment reveals a conserved ICE cutsite, resulting in a mature peptide of 162 amino acids. Thetrout IL-18 shares 41–45% similarity with known IL-18molecules and contains an IL-1 family signature motif....
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Báo cáo khoa học: Identification and expression analysis of an IL-18 homologue and its alternatively spliced form in rainbow trout (Oncorhynchus mykiss)

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