Báo cáo khoa hoc: Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? insights from characterization of D-amino acid oxidase

D-Amino acid oxidase (DAAO; EC 1.4.3.3) has been proposed to play amain role in the degradation ofD-serine, an allosteric activator of theN-methyl-D-aspartate-type glutamate receptor in the human brain, and to beassociated with the onset of schizophrenia.
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Báo cáo khoa hoc: Is rat an appropriate animal model to study the involvement of D-serine catabolism in schizophrenia? insights from characterization of D-amino acid oxidase