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Báo cáo khóa học: New activities of a catalytic antibody with a peroxidase activity

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In order to estimate the size of the cavity remaining aroundthe heme of the 3A3–microperoxidase 8 (MP8) hemo-abzyme,the formation of 3A3–MP8–Fe(II)-nitrosoalkanecomplexes upon oxidation of N-monosubstituted hydroxyl-amines was examined. This constituted a new reaction forhemoabzymes and is the first example of fully characterizedFe(II)–metabolite complexes of antibody–porphyrin. Also,via a comparison of the reactions with N-substituted hyd-roxylamines of various size and hydrophobicity,antibody3A3 was confirmed to bring about a partial steric hindranceon the distal face of MP8....
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Báo cáo khóa học: New activities of a catalytic antibody with a peroxidase activity

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