Báo cáo khoa học: Protein kinase C e phosphorylates keratin 8 at Ser8 and Ser23 in GH4C1 cells stimulated by thyrotropin-releasing hormone
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Protein kinase Ce (PKCe) is activated by thyrotropin-releasing hormone(TRH), a regulator of pituitary function in rat pituitary GH4C1 cells. Weanalyzed the downstream mechanism after PKCe activation. Exposure ofGH4C1cells to TRH or a phorbol ester increased the phosphorylation ofthree p52 proteins (p52a, p52b and p52c) and decreased the phosphoryla-tion of destrin and cofilin.
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Báo cáo khoa học: Protein kinase C e phosphorylates keratin 8 at Ser8 and Ser23 in GH4C1 cells stimulated by thyrotropin-releasing hormone
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Protein kinase C e phosphorylates keratin 8 at Ser8 and Ser23 in GH4C1 cells stimulated by thyrotropin-releasing hormone
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