Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90
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Ca2+loading of Jurkat and bovine aorta endothelium cells induces thedegradation of the neuronal and endothelial nitric oxide synthases that areselectively expressed in these cell lines. For neuronal nitric oxide synthase,this process involves a conservative limited proteolysis without appreciableloss of catalytic activity.
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Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Proteolytic degradation of nitric oxide synthase isoforms by calpain is modulated by the expression levels of HSP90
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