Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism
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Monolayer primary cultures of thyroid cells produce, in thepresence of insulin, a cytosolic inhibitor of thyroid peroxi-dase (TPO), lacto peroxidase (LPO), horseradishperoxidase(HRPO) and glutathione peroxidase (GPX). The inhibitor,localized in the cytosol, is thermostable and hydrophylic.Itsmolecularmass is less than2 kDa.The inhibitoryactivity,resistant to proteolytic and nucleolytic enzymes, disappearswith sodium metaperiodate treatment, as an oxidant ofcarbohydrates, supporting its oligosaccharide structure....
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Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism
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Báo cáo khoa học: Role of peroxidase inhibition by insulin in the bovine thyroid cell proliferation mechanism
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