Báo cáo khoa học: Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPcS
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The guanine nucleotide-binding protein Ras occurs in solution in twodifferent conformational states, state 1 and state 2 with an equilibriumconstant K12 of 2.0, when the GTP analogue guanosine-5¢-(b,c-imido)tri-phosphate or guanosine-5¢-(b,c-methyleno)triphosphate is bound to theactive centre.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPcS
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPcS
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