Báo cáo khoa học: Thiol reducing compounds prevent human amylin-evoked cytotoxicity
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Human amylin (hA) is a small fibrillogenic protein that is the major con-stituent of pancreatic islet amyloid, which occurs in most subjects withtype-2 diabetes mellitus (T2Dm). There is growing evidence that hA toxic-ity towards islet b-cells is responsible for their gradual loss of function inT2Dm. Preventing hA-mediated cytotoxicity has been proposed as a routeto halt the progression of this disease, although this has not yet been dem-onstratedin vivo.
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Báo cáo khoa học: Thiol reducing compounds prevent human amylin-evoked cytotoxicity
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Báo cáo khoa học: Thiol reducing compounds prevent human amylin-evoked cytotoxicity
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