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Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
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A new, less expensive, solvent-free procedure was developed for the synthesis of some new derivatives of various fused heterocyclic ring systems, namely azolopyridazine, azolotriazine, azinotriazine, thienopyridine, and pyrazolopyridine. The structures of the products prepared were established by their spectral data and elemental analyses. Eight compounds were evaluated for their in vitro antimicrobial activity. Some of the tested compounds exhibited moderate to significant antibacterial and antifungal activities.
Nội dung trích xuất từ tài liệu:
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
Nội dung trích xuất từ tài liệu:
Convenient method for synthesis of various fused heterocycles via utility of 4-acetyl-5-methyl-1-phenyl-pyrazole as precursor
Tìm kiếm theo từ khóa liên quan:
Journal of Chemistry Antimicrobial activities 4-acetyl-5-methyl-1-phenyl-pyrazole In vitro antimicrobial activity Heterocyclic ring systemsTài liệu liên quan:
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