Dose response of umeclidinium administered once or twice daily in patients with COPD: A randomised cross-over study
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Umeclidinium bromide (UMEC) is an inhaled long-acting muscarinic antagonist in development for chronic obstructive pulmonary disease (COPD). UMEC is a potent QD bronchodilator with geometric mean ED50 of 37 μg. A dose ordering over the range of UMEC 15.6–125 μg QD doses was observed, with UMEC 125 μg showing the greatest improvement in trough FEV1.
Nội dung trích xuất từ tài liệu:
Dose response of umeclidinium administered once or twice daily in patients with COPD: A randomised cross-over study
Nội dung trích xuất từ tài liệu:
Dose response of umeclidinium administered once or twice daily in patients with COPD: A randomised cross-over study
Tìm kiếm theo từ khóa liên quan:
BMC Pulmonary Medicine Chronic obstructive pulmonary disease Long-acting bronchodilators Long-acting muscarinic antagonist Confidence intervalGợi ý tài liệu liên quan:
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