Ebook Pathology of the developing mouse - a systematic approach: Part 1

Part 1 book "Pathology of the developing mouse - A systematic approach" includes content: The case for developmental pathology and developmental pathologists, essentials of mouse genetics and nomenclature, essential terminology for mouse developmental pathology studies, anatomy and physiology of the developing mouse and placenta,.... and other contents.
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Ebook Pathology of the developing mouse - a systematic approach: Part 1 Pathology of the Developing Mouse A Systematic Approach Edited by Brad Bolon Pathology of the Developing Mouse Pathology of the Developing Mouse A Systematic Approach Edited by Brad Bolon Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2015 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20141017 International Standard Book Number-13: 978-1-4200-7009-5 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the valid- ity of all materials or the consequences of their use. 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CCC is a not-for-profit organization that provides licenses and registration for a variety of users. For organizations that have been granted a photocopy license by the CCC, a separate system of payment has been arranged. Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identification and explanation without intent to infringe. Visit the Taylor & Francis Web site at http://www.taylorandfrancis.com and the CRC Press Web site at http://www.crcpress.com This book is dedicated to those hardy souls who seek understanding of large truths from small canvases, who aspire to discover universal principles within ever-changing flesh, who strive to build a healthier tomorrow for all by willingly paying the price of difficult learning today. In other words, this book is devoted to all of you who have already suffered, or will someday encounter, the delights and debacles of mouse developmental pathology. Contents Preface....................................................................................................................................................... ix Acknowledgments...................................................................................................................................... xi Editor.......................................................................................................................................................xiii Contributors.............................................................................................................................................. xv Section I  Introduction 1. The Case for Developmental Pathology and Developmental Pathologists.................................. 3 Brad Bolon Section II  Fundamentals of Mouse Developmental Biology 2. Essentials of Mouse Genetics and Nomenclature........................................................................ 13 Oded Foreman and Brad Bolon 3. Essential Terminology for Mouse Developmental Pathology Studies........................................ 27 Brad Bolon and Colin G. Rousseaux 4. Anatomy and Physiology of the Developing Mouse and Placenta.............................................. 39 Brad Bolon and Jerrold M. Ward 5. Teratogens and Teratogenic Mechanisms in Mouse Developmental Pathology....................... 99 Brad Bolon and Colin G. Rousseaux Section III  Experimental Methods in Mouse Developmental Pathology 6. Principles of Experimental Design for Mouse Developmental Pathology Studies..................117 Brad Bolon and Krista M.D. La Perle 7. Necropsy Sampling and Data Collection for Studying the Anatomy, Histology, and Pathology of Mouse Development.................................................................................................133 Susan Newbigging, Jerrold M. Ward, and Brad Bolon 8. Clinical Pathology Analysis in Developing Mice.........................................................................175 Kelli L. Boyd, Brad Bolon, and Denise I. Bounous 9. Histotechnological Processing of Developing Mice.................................................................... 195 Brad Bolon, Diane Duryea, and Julie F. Foley 10. Localization of Gene Expression in Developing Mice................................................................211 Jennifer M. Mele and Brad Bolon vii viii Contents 11. Protein Localization in Developing Mice.............................................. ...