Effects of hydrophobic and electrostatic interactions on the escape of nascent proteins at bacterial ribosomal exit tunnel
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We study the escape process of nascent proteins at the ribosomal exit tunnel of bacterial Escherichia coli by using molecular dynamics simulations with coarse-grained and atomistic models. It is shown that the effects of hydrophobic and electrostatic interactions on the protein escape at the E. coli’s tunnel are qualitatively similar to those obtained previously at the exit tunnel of archaeal Haloarcula marismortui, despite significant differences in the structures and interactions of the ribosome tunnels from the two organisms.
Nội dung trích xuất từ tài liệu:
Effects of hydrophobic and electrostatic interactions on the escape of nascent proteins at bacterial ribosomal exit tunnel
Nội dung trích xuất từ tài liệu:
Effects of hydrophobic and electrostatic interactions on the escape of nascent proteins at bacterial ribosomal exit tunnel
Tìm kiếm theo từ khóa liên quan:
Communications in Physics Post-translational escape Ribosomal exit tunnel Electrostatic and hydrophobic interactions Diffusion modelGợi ý tài liệu liên quan:
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