Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFβ inhibition
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Less than 11% of pancreatic cancer patients survive 5-years post-diagnosis. The unique biology of pancreatic cancer includes a significant expansion of its desmoplastic tumor microenvironment, wherein cancerassociated fibroblasts (CAFs) and their self-produced extracellular matrix are key components.
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Extracellular matrix Cancer-associated fibroblasts Cell-derived ECM Pancreatic cancerGợi ý tài liệu liên quan:
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