Genome-wide mapping of 5- hydroxymethyluracil in the eukaryote parasite Leishmania
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5-Hydroxymethyluracil (5hmU) is a thymine base modification found in the genomes of a diverse range of organisms. To explore the functional importance of 5hmU, we develop a method for the genome-wide mapping of 5hmU-modified loci based on a chemical tagging strategy for the hydroxymethyl group.
Nội dung trích xuất từ tài liệu:
Genome-wide mapping of 5- hydroxymethyluracil in the eukaryote parasite Leishmania
Nội dung trích xuất từ tài liệu:
Genome-wide mapping of 5- hydroxymethyluracil in the eukaryote parasite Leishmania
Tìm kiếm theo từ khóa liên quan:
Genome Biology 5-Hydroxymethyluracil 5-Formyluracil Genome-wide mapping Leishmania major Leishmania donovaniTài liệu liên quan:
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