Multi-scale simulations of membrane proteins: The case of bitter taste receptors
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In addition, they suggest a two-binding site architecture in hTAS2R46, consisting of the usual orthosteric site together with a “vestibular” site toward the extracellular space, as observed in other GPCRs. The presence of the vestibular site may help to discriminate among the wide spectrum of bitter ligands.
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Multi-scale simulations of membrane proteins: The case of bitter taste receptors
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Multi-scale simulations of membrane proteins: The case of bitter taste receptors
Tìm kiếm theo từ khóa liên quan:
Advanced materials and devices G-protein coupled receptor Bitter taste receptor Molecular mechanics Coarse grained simulationsTài liệu liên quan:
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