PCalign: A method to quantify physicochemical similarity of protein-protein interfaces
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Structural comparison of protein-protein interfaces provides valuable insights into the functional relationship between proteins, which may not solely arise from shared evolutionary origin. A few methods that exist for such comparative studies have focused on structural models determined at atomic resolution, and may miss out interesting patterns present in large macromolecular complexes that are typically solved by low-resolution techniques.
Nội dung trích xuất từ tài liệu:
PCalign: A method to quantify physicochemical similarity of protein-protein interfaces
Nội dung trích xuất từ tài liệu:
PCalign: A method to quantify physicochemical similarity of protein-protein interfaces
Tìm kiếm theo từ khóa liên quan:
BMC Bioinformatics Protein-protein interactions Interface comparison Structural bioinformatics Convergent evolutionGợi ý tài liệu liên quan:
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