Summary of Chemistry doctoral thesis: Study on chemical constituents, biological activities of conifer species Dacrycarpus imbricatus and Fokienia hodginsii

The objective of the thesis: Study on the chemical constituents of the species Dacrycarpus imbricatus (Blume) de Laub, Fokienia hodginsii (Dunn) Henry a. et Thomas; investigation in to their biological activities.
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Summary of Chemistry doctoral thesis: Study on chemical constituents, biological activities of conifer species Dacrycarpus imbricatus and Fokienia hodginsiiMINISTRY OF EDUCATION AND VIETNAM ACADEMY TRAINING OF SCIENCE AND TECHNOLOGY GRADUATE UNIVERSITY SCIENCE AND TECHNOLOGY ---------------------------- DANG VIET HAU STUDY ON CHEMICAL CONSTITUENTS, BIOLOGICAL ACTIVITIES OF CONIFER SPECIES:DACRYCARPUS IMBRICATUS AND FOKIENIA HODGINSII Major: Organic Chemistry Code: 62 44 01 14 SUMMARY OF CHEMISTRY THE DOCTORAL THESIS HA NOI - 2017 Thesis was completed at: Institute of Chemistry Vietnam Academy of Science & TechnologyAdvisers: 1. Assoc. Prof. Dr. Trinh Thi Thuy Institute of Chemistry- Vietnam Academy of Science & Technology 2. Dr. Tran Van Loc Institute of Chemistry- Vietnam Academy of Science & Technology 1st Reviewer: .............................................................................. 2nd Reviewer: ............................................................................. 3rd Reviewer: ............................................................................... The dissertation will be defended at: Graduate University Science andTechnology - Vietnam Academy of Science & Technology- No. 18 Hoang Quoc Viet - Cau Giay - Hanoi. At............hour.............day............month............ 2017Thesis can be found in: -The library of Graduate University Science And Technology -National Library of Vietnam INTRODUCTION 1. The urgency of the thesis Thanks for industrial development, human life is increasinglyimproving. However, the downside of this development is environmentalcatastrophe. Moreover, abuse of chemicals and medicines plant protectionin agriculture and food industry, together with the resistance of the virusspecies, the bacteria, the variation of this species do encounter evidence ofhuman diseases such as cancer, HIV/AIDS, heart disease, diabetes, SARS,or recent viral fewers. To deal with the challenges of constant evolution of life, scientistsmust continuously invent new medicines providing selected effects,effective, and affordable to both human patients and the conservation ofrare plant and animal species. According to scientists, studying the natureand mimic-nature are the best the way for human being to exist and adaptto their living environments. One of the approaches is researching newstructures with potential activity that be able to be developed intomedicines for humans, livestock, and crops from natural compounds. Overmillions of years of evolution, these natural compounds have mounted up aflexible compatibility and relatively suitability with living organisms;especially, they also contain less toxic and perform morefriendly toenvironment. Located in the tropical monsoon climate, Vietnam has extremelydiverse vegetation and abundant with approximately 13,000 species , ofwhich 309 branches and 4,000 species can be adopted to make drugs. As aresult, these are invaluable natural resources of the country. Althoughthere are many types of herbs that can be used to make medicines forpeople, livestock and crops, their economic performance is still limitedbecause the exploit and usage are still based on folk experience. Based on this scientific background, we chose the project Study onchemical constituents, biological activities of conifer species Dacrycarpusimbricatus and Fokienia hodginsii. 2. The objective of the thesis - Study on the chemical constituents of the species Dacrycarpusimbricatus (Blume) de Laub, Fokienia hodginsii (Dunn) Henry a. etThomas. - Investigation in to their biological activities 3. The main content of the thesis 1 - Purification and isolation of compounds from crude extracts ofthese species is techniques as column chromatography, flash columnchromatography, etc. - Determine structure of the pure compounds by the combination ofspectral methods such as IR, MS, 1D-2D-NMR, NMR, etc. - Some isolated compounds were tested biological activities in orderto discover potential compounds. Chapter 1: OVERVIEW 1.1. Characteristics of plant and study of the genenusDacrycarpus, family Podocarpaceae 1.1.1. Characteristics of plant genenus Dacrycarpus 1.1.1.1. Characteristics of plant species Dacrycarpus imbricatus 1.1.1.2. Characteristics of plant species Dacrycarpus dacrydioides 1.1.1.3. Characteristics of plant species Dacrycarpus vieillardii 1.1.2. Used in traditional medicine 1.1.3. The chemical constituents and ...