The study on clinical phenotypes of pulmonary hypertension due to left heart disease at pre-operation time in patients with isolated mitral valve replacement or double valve replacement

We aimed at describing the different hemodynamic phenotypes of patients with pulmonary hypertension due to left heart disease before mitral valve replacement and/or concomitant aortic valve replacement and characterizing the impact of pulmonary hemodynamics on RV function. Subjects and method: 67 patients with pulmonary hypertension related to left heart diseases who underwent elective mitral valve replacement and/or aortic valve replacement enrolled in this prospective study from April, 2017 to April, 2018 at Hue Heart Center. Results and conclusions: Prevalence of three subgroups of patients pulmonary hemodynamics: isolated post-capillary pulmonary hemodynamics (Ipc - pulmonary hypertension); combined post- and pre-capillary pulmonary hypertension (Cpc - pulmonary hypertension); intermediate pulmonary hemodynamics were 43.2%, 28.4% and 28.4%, respectively. Cpc pulmonary hemodynamics presented with slightly higher weight and body mass index than intermediate patients (p < 0.05).
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The study on clinical phenotypes of pulmonary hypertension due to left heart disease at pre-operation time in patients with isolated mitral valve replacement or double valve replacement