A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape
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Immune checkpoint inhibitor (ICI) therapy has revolutionized the treatment of many cancers. However, the limited population that benefits from ICI therapy makes it necessary to screen predictive biomarkers for stratifying patients. Currently, many biomarkers, such as tumor mutational burden (TMB), have been used in the clinic as indicative biomarkers.
Nội dung trích xuất từ tài liệu:
A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape
Nội dung trích xuất từ tài liệu:
A mutation-based gene set predicts survival benefit after immunotherapy across multiple cancers and reveals the immune response landscape
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Genome medicine Tumor microenvironment Immune response Immune checkpoint inhibitor Indicative biomarkers Anti-PD-L1Gợi ý tài liệu liên quan:
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