Regulation of HHLA2 expression in kidney cancer and myeloid cells
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The immune checkpoint HERV-H LTR-associating 2 (HHLA2) is expressed in kidney cancer and various other tumor types. Therapeutics targeting HHLA2 or its inhibitory receptor KIR3DL3 are being developed for solid tumors, including renal cell carcinoma (RCC). However, the regulation of HHLA2 expression remains poorly understood.
Nội dung trích xuất từ tài liệu:
Regulation of HHLA2 expression in kidney cancer and myeloid cells
Nội dung trích xuất từ tài liệu:
Regulation of HHLA2 expression in kidney cancer and myeloid cells
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Kidney cancer Tumor microenvironment HERV-H LTR-associating 2 Inhibitory receptor KIR3DL3 Solid tumorsTài liệu liên quan:
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