Danh mục

A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer

Số trang: 9      Loại file: pdf      Dung lượng: 596.36 KB      Lượt xem: 3      Lượt tải: 0    
Xem trước 2 trang đầu tiên của tài liệu này:

Thông tin tài liệu:

The mutation in KRAS exon 2 is a validated biomarker of resistance to anti-epidermal growth factor receptor (EGFR) therapy in metastatic colorectal cancer (mCRC). Several reports have confirmed associations of other RAS mutations with resistance to anti-EGFR therapy. However, the impact of BRAF and PIK3CA mutations on the efficacy of anti-EGFR therapy remains controversial.
Nội dung trích xuất từ tài liệu:
A retrospective observational study of clinicopathological features of KRAS, NRAS, BRAF and PIK3CA mutations in Japanese patients with metastatic colorectal cancer

Tài liệu được xem nhiều: