Alterations in the mammary gland and tumor microenvironment of formerly obese mice
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Obesity is a risk factor for breast cancer, and women with obesity that develop breast cancer have a worsened prognosis. Within the mammary gland, obesity causes chronic, macrophage-driven inflammation and adipose tissue fibrosis. Weight loss is a recommended intervention to resolve obesity, but the impact of weight loss on the mammary gland microenvironment and in tumors has not been well identified.
Nội dung trích xuất từ tài liệu:
Alterations in the mammary gland and tumor microenvironment of formerly obese mice
Nội dung trích xuất từ tài liệu:
Alterations in the mammary gland and tumor microenvironment of formerly obese mice
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BMC Cancer Mammary gland Weight loss Breast cancer Myeloid progenitor cells Obesity causes chronicTài liệu liên quan:
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