Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway
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Although thiazolidinediones (TZDs) are potent promoters of adipogenesisin the preadipocyte, they induce apoptosis in several other cell types,such as cancer cells, endothelial cells and T-lymphocytes. In this study,we investigated the proapoptotic effect of TZDs in mature 3T3-L1adipocytes, which express high levels of the peroxisome proliferator-acti-vated receptor-c (PPARc) protein.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: 3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-c-dependent and mediated by the caspase-3-dependent apoptotic pathway
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