Báo cáo khoa học: A functional polymorphism at the transcriptional initiation site in b2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of b2-glycoprotein I
Số trang: 9
Loại file: pdf
Dung lượng: 254.43 KB
Lượt xem: 7
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
Humanb2-glycoprotein I (b2GPI), also known as apolipo-protein H, has been implicated in haemostasis and the pro-duction ofanti-phospholipid antibodies. There is a widerange ofinterindividual variation in b2GPI plasma levelsthat is thought to be under genetic control, but itsmolecularbasis remains unknown. To understand the genetic basis ofb2GPI variation, we analyzed the 5¢ flanking region oftheb2GPIgene for mutation detection by DHPLC and identi-fied a point mutation at the transcriptional initiation site()1CfiA) with a carrier frequency of 12.1%. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: A functional polymorphism at the transcriptional initiation site in b2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of b2-glycoprotein I
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: A functional polymorphism at the transcriptional initiation site in b2-glycoprotein I (apolipoprotein H) associated with reduced gene expression and lower plasma levels of b2-glycoprotein I
Tìm kiếm theo từ khóa liên quan:
scientific reports Report medicine traditional medicine breast cancer biological activities environmental medicineTài liệu liên quan:
-
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases
10 trang 40 0 0 -
12 trang 39 0 0
-
35 trang 38 0 0
-
7 trang 33 0 0
-
8 trang 33 0 0
-
CYP4B1 polymorphisms and the risk of breast cancer in Chinese women: A case-control study
14 trang 32 0 0 -
21 trang 32 0 0
-
22 trang 32 0 0
-
Báo cáo khoa học: Parsing in the Ahsmmeeofa Comldete Lexicon
2 trang 31 0 0 -
EVI1 expression in early-stage breast cancer patients treated with neoadjuvant chemotherapy
10 trang 30 0 0