Báo cáo khoa học: A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
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Mitogen-activated protein kinase (MAPK) signaling determines crucial cellfate decisions in most cell types, and mediates cellular transformation inmany types of cancer. The activity of MAPK is controlled by reversiblephosphorylation, and the quantitative characteristics of MAPK activationdetermine the cellular response.
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Báo cáo khoa học: A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
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Báo cáo khoa học: A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
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