Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia
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The effects of physiologically relevant hypoxia on thecatalytic activity of cytochromecoxidase (CytOX), mito-chondrial gene expression, and both nuclear and mito-chondrial encoded CytOX mRNA levels were investigatedin murine monocyte macrophages, mouse C2C12 skeletalmyocytes and rat adrenal pheochromocytoma PC12 cells.Our results suggest a coordinated down regulation of mito-chondrial genome-coded CytOX I and II and nucleargenome-codedCytOX IV andVbmRNAs during hypoxia.
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Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia
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