Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding
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Human glutamate carboxypeptidase II (GCPII) is aco-catalytic metallopeptidase and its putative catalyticdomain is homologous to the aminopeptidases fromVibrioproteolyticus and Streptomyces griseus.In humans, theenzyme is expressed predominantly in the nervous systemand theprostate.Theprostate form, termedprostate-specificmembraneantigen, is overexpressed inprostate cancer and isused as a diagnostic marker of the disease.II
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Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding
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Báo cáo khoa học: Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding
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