Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle
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Cyclins are the essential regulatory subunits of cyclin-dependent proteinkinases. They accumulate and disappear periodically at specific phases ofthe cell cycle. Here we investigated whether variations in cyclin mRNAlevels in exponentially growing cells can be attributed to changes in mRNAstability. Mouse EL4 lymphoma cells and 3T3 fibroblasts were synchron-ized by elutriation or cell sorting.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Analysis of the contribution of changes in mRNA stability to the changes in steady-state levels of cyclin mRNA in the mammalian cell cycle
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