Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor
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Recently, we have shown that the biosynthesis of androste-nol, a potential endogenous ligand for the orphan receptorsconstitutive androstane receptor and pregnane-X-receptor,requires the presence of enzymes of the steroidogenic path-way, such as 3b-hydroxysteroid dehydrogenase, 5a-reduc-tase and 3a-hydroxysteroid dehydrogenase.
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Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor
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