Báo cáo khoa học: b-Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH
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Amyloid protein (Ab1–40) aggregation and conformationwas examined using native and sodium dodecyl sulfate/polyacrylamide gel electrophoresis,and the results com-pared with those obtained by atomic force microscopy,and with Congo red binding,sedimentation and turbidityassays. The amount of Ab aggregation measured wasdifferent,depending upon the method used. Incubationfor 15 min at pH 5.0 or in the presence of Fe2+,Cu2+orZn2+did not alter the level of Aboligomers observed onSDS and native gels....
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Báo cáo khoa học: b-Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH
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Báo cáo khoa học: b-Amyloid protein oligomers induced by metal ions and acid pH are distinct from those generated by slow spontaneous ageing at neutral pH
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