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Báo cáo khoa học: Characterization of depolarization and repolarization phases of mitochondrial membrane potential fluctuations induced by tetramethylrhodamine methyl ester photoactivation

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Depolarization and repolarization phases (D and R phases, respectively) ofmitochondrial potential fluctuations induced by photoactivation of thefluorescent probe tetramethylrhodamine methyl ester (TMRM) were ana-lyzed separately and investigated using specific inhibitors and substrates.The frequency of R phases was significantly inhibited by oligomycin andaurovertin (mitochondrial ATP synthase inhibitors), rotenone (mitochond-rial complex I inhibitor) and iodoacetic acid (inhibitor of the glycolyticenzyme glyceraldehyde-3-phosphate dehydrogenase)....
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Báo cáo khoa học: Characterization of depolarization and repolarization phases of mitochondrial membrane potential fluctuations induced by tetramethylrhodamine methyl ester photoactivation

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