Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity
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The TPaand TPbisoforms of the human thromboxane A2 receptor (TP)arise by differential splicing but are under the transcriptional control oftwo distinct promoters, termed Prm1 and Prm3, respectively (Coyle et al.2002Eur J Biochem269, 4058–4073). The aim of the current study was todetermine the key factors regulating TPbexpression by functionally charac-terizing Prm3, identifying the core promoter and the cis-acting elementsregulating basal Prm3 activity.
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Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Characterization of promoter 3 of the human thromboxane A2 receptor gene A functional AP-1 and octamer motif are required for basal promoter activity
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