Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin
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Nephrin is a signalling cell–cell adhesion protein of the Ig superfamily andthe first identified component of the slit diaphragm that forms the criticaland ultimate part of the glomerular ultrafiltration barrier. The extracellulardomains of the nephrin molecules form a network of homophilic andheterophilic interactions building the structural scaffold of the slit dia-phragm between the podocyte foot processes.
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Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Characterization of the interactions of the nephrin intracellular domain Evidence that the scaffolding protein IQGAP1 associates with nephrin
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