Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA
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Peroxiredoxins belong to a family of antioxidant proteins that neutralizereactive oxygen species. One member of this family, peroxiredoxin I(PRDX1), suppresses DNA oxidation. Peroxiredoxin V (PRDX5) has beencloned as a transcriptional corepressor, as a peroxisomal⁄mitochondrialantioxidant protein, and as an inhibitor of p53-dependent apoptosis.
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Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA
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