Báo cáo khoa học: D88A mutant of cytochrome P450nor provides kinetic evidence for direct complex formation with electron donor NADH
Số trang: 8
Loại file: pdf
Dung lượng: 534.70 KB
Lượt xem: 8
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
The haem-distal pocket of nitric oxide reductase cyto-chrome P450 contains many Arg and Lys residues that areclustered to form a putative access channel for NADH.Asp88 is the sole negatively charged amino acid in thispositive charge cluster, and thus it would be interesting toknow its functional role. Here we found the intriguingphenomenon that mutation at this site of P450nor (D88Aor D88V) considerably decreased the overall nitric oxidereductase activity without blocking the reducing half reac-tion in which the ferric enzyme–NO complex is reducedwith NADH to yield a specific intermediate (I). ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: D88A mutant of cytochrome P450nor provides kinetic evidence for direct complex formation with electron donor NADH
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: D88A mutant of cytochrome P450nor provides kinetic evidence for direct complex formation with electron donor NADH
Tìm kiếm theo từ khóa liên quan:
Report medicine traditional medicine scientific reports molecular Biology tumor cells AntimicrobialTài liệu liên quan:
-
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases
10 trang 39 0 0 -
Ebook Animal models of epilepsy, methods and innovations: Part 1
146 trang 37 0 0 -
8 trang 33 0 0
-
7 trang 33 0 0
-
Báo cáo khoa học: Parsing in the Ahsmmeeofa Comldete Lexicon
2 trang 31 0 0 -
Báo cáo khoa học: Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry
9 trang 29 0 0 -
10 trang 28 0 0
-
14 trang 28 0 0
-
Ebook Bovine viral diarrhea virus - Diagnosis, management, and control: Part 1
108 trang 28 0 0 -
Ebook The cell - A molecular approach (4/E): Part 2
272 trang 27 0 0