Báo cáo khoa học: Determinants of the nucleocytoplasmic shuttling of muscle glycogen synthase
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Muscle glycogen synthase (MGS) presents a nuclear speckled pattern inprimary cultured human muscle and in 3T3-L1 cells deprived of glucoseand with depleted glycogen reserves. Nuclear accumulation of the enzymecorrelates inversely with cellular glycogen content. Although the glucose-induced export of MGS from the nucleus to the cytoplasm is blocked byleptomycin B, and therefore mediated by CRM1, no nuclear export signalwas identified in the sequence of the protein.
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Báo cáo khoa học: Determinants of the nucleocytoplasmic shuttling of muscle glycogen synthase
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Báo cáo khoa học: Determinants of the nucleocytoplasmic shuttling of muscle glycogen synthase
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