Báo cáo khoa học: Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes
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NTPDase1 and NTPDase2 are two related plasma mem-brane-located enzymes involved in the extracellular degra-dation of nucleoside 5¢-tri- and -diphosphates. They differregarding their hydrolysis ratios for ATP and ADP. Bothenzymes have a predicted transmembrane domain close tothe N- and C-terminus, respectively, connected by anextensive extracellular domain that carries the active site.Weexpressed the rat-derived enzymes inXenopus laevisoocytesand analyzed their quarternary structure.
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Báo cáo khoa học: Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes
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Báo cáo khoa học: Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes
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