Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/–
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The lipolysis stimulated receptor (LSR) recognizes apo-lipoprotein B/E-containing lipoproteins in the presence offree fattyacids, and is thought tobe involved in the clearanceof triglyceride-rich lipoproteins (TRL). The distribution ofLSR in mice was studied by Northern blots, quantitativePCR and immunofluorescence. In the adult,LSRmRNAwas detectable in all tissues tested except muscle and heart,and was abundant in liver, lung, intestine, kidney, ovariesand testes. During embryogenesis, LSR mRNA wasdetectable at 7.5 days post-coitum (E7) and increased up toE17 inparallel toprothrombin, a livermarker. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/–
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Distribution of the lipolysis stimulated receptor in adult and embryonic murine tissues and lethality of LSR–/–
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