Báo cáo khoa học: Dynamic reorganization of the motor domain of myosin subfragment 1 in different nucleotide states
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Atomic models of the myosin motor domain with differentbound nucleotides have revealed the open and closed con-formationsof the switch2 element [Geeves,M.A.&Holmes,K.C. (1999)Annu. Rev. Biochem.68, 687–728]. The twoconformations are in dynamic equilibrium, which is con-trolled by the bound nucleotide. In the present work weattempted to characterize the flexibilityof themotor domainin the open and closed conformations in rabbit skeletalmyosin subfragment 1.
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Báo cáo khoa học: Dynamic reorganization of the motor domain of myosin subfragment 1 in different nucleotide states
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Dynamic reorganization of the motor domain of myosin subfragment 1 in different nucleotide states
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