Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair
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Ionizing radiation, oxidative stress and endogenous DNA-damage pro-cessing can result in a variety of single-strand breaks with modified 5¢and⁄or 3¢ ends. These are thought to be one of the most persistentforms of DNA damage and may threaten cell survival. This studyaddresses the mechanism involved in recognition and processing ofDNA strand breaks containing modified 3¢ ends.
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Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: End-damage-specific proteins facilitate recruitment or stability of X-ray cross-complementing protein 1 at the sites of DNA single-strand break repair
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