Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line
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Endoplasmic reticulum-associated degradation of newlysynthesized glycoproteins has been demonstrated previouslyusing various mammalian cell lines. Depending on the celltype, glycoproteins bearingMan9 glycans and glycoproteinsbearing Man5 glycans can be efficiently degraded. Awidevariety of variables can lead to defective synthesis of lipid-linked oligosaccharides and, therefore, in mammalian cells,species derived fromMan9GlcNAc2 orMan5GlcNAc2 areoften recovered on newly synthesized glycoproteins. ...
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Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line
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Báo cáo khóa học: Endoplasmic reticulum-associated degradation of glycoproteins bearing Man5GlcNAc2 and Man9GlcNAc2 species in the MI8-5 CHO cell line
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