Báo cáo khoa học: Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy
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While cardiac hypertrophy elicited by pathological stimuli eventually leadsto cardiac dysfunction, exercise-induced hypertrophy does not. This sug-gests that a beneficial hypertrophic phenotype exists. In search of an under-lying molecular substrate we used microarray technology to identifycardiac gene expression in response to exercise. Rats exercised for sevenweeks on a treadmill were characterized by invasive blood pressure mea-surements and echocardiography.
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Báo cáo khoa học: Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Expression profiling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy
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