Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation
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The basic helix-loop-helix transcription factor DEC1 isexpressed in a circadian manner in the suprachiasmaticnucleus where it seems to play a role in regulating themammalian circadian rhythm by suppressing theCLOCK/BMAL1-activated promoter. The interaction ofDEC1 with BMAL1 has been suggested as one of themolecular mechanisms of the suppression [Honma, S.,Kawamoto, T., Takagi, Y., Fujimoto, K., Sato, F.,Noshiro, M., Kato, Y. & Honma, K. (2002)Nature419,841–844].
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Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation
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Báo cáo khoa học: Functional analysis of the basic helix-loop-helix transcription factor DEC1 in circadian regulation
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