Báo cáo khoa học: Haptoglobin binds the antiatherogenic protein apolipoprotein E – impairment of apolipoprotein E stimulation of both lecithin: cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
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Haptoglobin (Hpt) binds apolipoprotein A-I (ApoA-I), and impairs itsstimulation of lecithin:cholesterol acyltransferase (LCAT). LCAT plays amajor role in reverse cholesterol transport (RCT). Apolipoprotein E(ApoE), like ApoA-I, promotes different steps of RCT, including LCATstimulation.
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Báo cáo khoa học: Haptoglobin binds the antiatherogenic protein apolipoprotein E – impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
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Báo cáo khoa học: Haptoglobin binds the antiatherogenic protein apolipoprotein E – impairment of apolipoprotein E stimulation of both lecithin:cholesterol acyltransferase activity and cholesterol uptake by hepatocytes
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