Báo cáo khoa học: Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases
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Diadenosine polyphosphates (ApnAs) act as extracellularsignaling molecules in a broad variety of tissues. They wereshown to be hydrolyzed by surface-located enzymes in anasymmetric manner, generating AMP and Apn-1 fromApnA. The molecular identity of the enzymes responsibleremains unclear.We analyzed the potential ofNPP1, NPP2,and NPP3, the three members of the ecto-nucleotide pyro-phosphatase/phosphodiesterase family, to hydrolyze thediadenosine polyphosphates diadenosine 5¢,5¢¢¢-P1,P3-triphosphate (Ap3A),...
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Báo cáo khoa học: Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases
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Báo cáo khoa học: Hydrolysis of diadenosine polyphosphates by nucleotide pyrophosphatases/phosphodiesterases
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